Gene UniProt Gene Full Name Protein Class N. diseases g DSI g DPI g pLI Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
O60674 Janus kinase 2 Kinase 644 0.385 0.885 0.65 0.300 None 0.979 516 12 2005 2020
Entrez Id: 25
Gene Symbol: ABL1
ABL1
P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 395 0.432 0.923 1.00 0.100 None 0.975 159 0 1993 2020
Entrez Id: 811
Gene Symbol: CALR
CALR
P27797 calreticulin Calcium-binding protein 487 0.413 0.923 0.89 0.100 None 0.980 102 0 2014 2020
Entrez Id: 4352
Gene Symbol: MPL
MPL
P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 222 0.510 0.692 4.1E-09 0.500 None 0.979 95 5 1995 2020
Entrez Id: 6646
Gene Symbol: SOAT1
SOAT1
P35610 sterol O-acyltransferase 1 Enzyme 389 0.424 0.846 7.4E-10 0.100 None 1.000 33 0 2006 2020
Entrez Id: 7066
Gene Symbol: THPO
THPO
P40225 thrombopoietin 185 0.513 0.692 0.20 0.080 None 1.000 8 0 1995 2020
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
Q99062 colony stimulating factor 3 receptor Signaling 120 0.550 0.692 1.5E-10 0.060 None 1.000 6 1 2009 2020
Entrez Id: 2623
Gene Symbol: GATA1
GATA1
P15976 GATA binding protein 1 264 0.483 0.808 0.95 0.060 None 1.000 6 0 2005 2020
Entrez Id: 29072
Gene Symbol: SETD2
SETD2
Q9BYW2 SET domain containing 2, histone lysine methyltransferase Epigenetic regulator 447 0.424 0.846 1.00 0.030 None 1.000 3 0 2016 2020
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 1044 0.327 0.923 0.98 0.030 None 0.667 3 0 2017 2020
Entrez Id: 79885
Gene Symbol: HDAC11
HDAC11
Q96DB2 histone deacetylase 11 Epigenetic regulator 54 0.636 0.654 6.9E-03 0.020 None 1.000 2 0 2012 2020
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
O14965 aurora kinase A Kinase 245 0.475 0.731 0.87 0.020 None 1.000 2 0 2019 2020
Entrez Id: 10013
Gene Symbol: HDAC6
HDAC6
Q9UBN7 histone deacetylase 6 Epigenetic regulator 288 0.465 0.846 1.00 0.010 None 1.000 1 0 2020 2020
Entrez Id: 613
Gene Symbol: BCR
BCR
P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 392 0.431 0.885 0.99 0.100 None 0.942 69 0 1992 2019
Entrez Id: 5159
Gene Symbol: PDGFRB
PDGFRB
P09619 platelet derived growth factor receptor beta Kinase 492 0.416 0.846 0.90 0.300 None 1.000 24 0 2003 2019
Entrez Id: 54790
Gene Symbol: TET2
TET2
Q6N021 tet methylcytosine dioxygenase 2 362 0.458 0.808 4.3E-54 0.100 None 0.958 24 1 2009 2019
Entrez Id: 171023
Gene Symbol: ASXL1
ASXL1
Q8IXJ9 ASXL transcriptional regulator 1 296 0.482 0.808 1.3E-14 0.300 None 1.000 13 0 2010 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
P04637 tumor protein p53 Transcription factor 2494 0.236 0.962 0.53 0.100 None 0.917 12 0 1993 2019
Entrez Id: 3716
Gene Symbol: JAK1
JAK1
P23458 Janus kinase 1 Kinase 239 0.474 0.769 1.00 0.100 None 1.000 12 0 2009 2019
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
O14543 suppressor of cytokine signaling 3 Enzyme modulator 375 0.434 0.808 0.75 0.080 None 1.000 8 1 2008 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD
O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1119 0.319 0.885 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1101 0.320 0.885 1.4E-06 0.080 None 1.000 8 0 2012 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1511 0.292 0.923 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1083 0.322 0.885 1.00 0.080 None 1.000 8 0 2012 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
P48735 isocitrate dehydrogenase (NADP(+)) 2 380 0.434 0.808 0.88 0.070 None 1.000 7 1 2010 2019